Publications

  (ID: 0000-0003-3964-2150)

2018

[24] Wychowaniec J., Iliut M., Zhou M., Moffat J., Elsawy M., Pinheiro W., Hoyland J., Miller A., Vijayaraghavan A., Saiani A. Designing peptide / graphene hybrid hydrogels through fine tuning of molecular interactions, Biomacromolecules 2018 (Accepted) DOI: 10.1021/acs.biomac.6b01693

[23] Elsawy M., Miller A., Saiani A., Peptide Hydrogels: A Versatile Platform for Drug Delivery, oral presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2018, Bradford, UK

[22] Moinuddin N., Chhabria V., Wychowaniec J., Patil-Sen Y., Forbes R., Saiani A., Elsawy M., Interfacial self-assembly of short peptides into fibrillised microspheres: A potential drug delivery vehicle, poster presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2018, Bradford, UK

2017

[21] Morris O., Elsawy M., Fairclough M., Williams K., McMahon A., Grigg J., Forster D., Miller A., Saiani A., Prenant C., In vivo characterisation of a therapeutically relevant self-assembling 18F- labelled β-sheet forming peptide and its hydrogel using positron emission tomography, Journal of Labelled Compounds and Radiopharmaceuticals 2017; 60: 481-488. DOI: 10.1002/jlcr.3534

[20] Milani A., Fielding L., Greensmith P., Adlam D., Freemont A., Hoyland J., Hodson N., Elsawy M., Miller A., Ratcliffe L., Mykhaylyk O., Armes S., Saunders B., Anisotropic pH-responsive Hydrogels containing Soft or Hard Rod-like Particles Assembled using Low Shear, Chemistry of Materials 2017; 29: 3100-3110 (cover page). DOI: 1021/acs.chemmater.7b00110

[19] Gao J., Tang C., Elsawy M., Smith A., Miller A., Saiani A., Controlling self-assembling peptide hydrogel properties through network topology,  Biomacromolecules 2017;18: 826–834. DOI:1021/acs.biomac.6b01693

[18] Elsawy M., Castillo-Díaz L., Wychowaniec J., Miller A., Saiani A., Designing self-assembling β-sheet peptide nanofibers for controlling Doxorubicin release kinetics from hydrogels by fine-tuning peptide-drug non-covalent molecular interactions, poster presentation at The Bioinspired Materials Conference 2017, Manchester, UK

2016

[17] Elsawy M., Smith A., Miller A., Saiani A., Modification of hydrophobic face of β-sheet forming peptide: effect on self-assembly and gelation, Langmuir 2016; 32: 4917-4923. DOI: 1021/acs.langmuir.5b03841

[16] Castillo-Díaz L., Elsawy M., Saiani A., Gough J., Miller A., Osteogenic differentiation of human mesenchymal stem cells promotes mineralization within a biodegradable peptide-hydrogel, Journal of Tissue Engineering 2016; 7: 1-15. DOI: 1177/2041731416649789

[15] Elsawy M., Castillo-Díaz L., Wychowaniec J., Miller A., Saiani A., Tailoring peptide hydrogels for controlling drug release kinetics, oral presentation at Institute of Physics: The Physics of Soft and Biological Matter Conference 2016, Cambridge, UK

[14] Elsawy M., Castillo-Díaz L., Wychowaniec J., Miller A., Saiani A., Controlling Doxorubicin release from β-sheet peptide hydrogels by finely-tuning drug-peptide interactions, oral presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2016, Birmingham, UK

2015

[13] Elsawy M., Martin L., Tikhonova I., Walker B., Smac-derived aza-peptide as an aminopeptidase-resistant XIAP BIR3 antagonist, Protein & Peptide Letters 2015; 22: 836-843. DOI: 2174/0929866522666150622101626

[12] Elsawy M., Castillo-Díaz L., Miller A., Saiani A., Stimuli-responsive β-sheet forming  peptide hydrogels as drug delivery systems for controlled drug release, oral presentation at Materials Research Society Spring Meeting & Exhibition 2015, San Francisco, California, USA

[11] Elsawy M., Castillo-Díaz L., Miller A., Saiani A., Tailoring drug release kinetics from peptide hydrogels, poster presentation at RAMS Conference 2015, Coventry, UK

[10] Elsawy M., Castillo-Díaz L., Miller A., Saiani A., β-sheet peptide hydrogels as vehicles for drug delivery, poster presentation at Biomaterials Showcase 2015, Manchester, UK

[9] Castillo-Díaz L., Elsawy M., Saiani A., Gough J., Miller A., Osteogenic differentiation of human mesenchymal stem cells within a beta-sheet peptide hydrogel induces mineralisation in vitro, poster presentation at The 9th UK Mesenchymal Stem Cell Meeting 2015, Manchester, UK.

[8] Elsawy M., Miller A., Saiani A., pH-triggered β-hairpin peptide hydrogel formation through intramolecular β-sheet-turn-sheet self-assembly, poster presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2015, London, UK

2014

[7] Elsawy M., Smith A., Miller A., Saiani A., Chemically cross-linked peptide-based hydrogels with potential biomedical applications, poster presentation at 26th Annual Conference European Society of Biomaterials 2014, Liverpool, UK

[6] Elsawy M., Smith A., Miller A., Saiani A., Covalently cross-linked peptide-based hydrogels with potential biomedical applications, poster presentation at RAMS Conference 2014, Bath, UK

2013

[5] Elsawy M., Martin L., Tikhonova I., Walker B., Solid phase synthesis of Smac/DIABLO-derived peptides using a “Safety-Catch” resin: identification of potent XIAP BIR3 antagonists, Bioorganic and Medicinal Chemistry 2013; 21: 5004-5011. DOI: 1016/j.bmc.2013.06.055

2012

[4] Elsawy M., Hewage C., Walker B., Racemisation of N-Fmoc phenylglycine under mild microwave-SPPS and conventional stepwise SPPS conditions: attempts to develop strategies for overcoming this, Journal of Peptide Science 2012; 18: 302-311. DOI: 1002/psc.2398

[3] Elsawy M., Martin L., Walker B., Lactam bridge stabilised Bim peptides promote apoptosis in PC3 prostate cancer cells through Bax activation at a novel trigger site: a promising strategy for cancer therapy, poster presentation at Irish Association for Cancer Research Annual Conference 2012, Belfast, UK

[2] Elsawy M., Martin L., Walker B., Heterogeneous backbone α/β Bim-derived peptide foldamers trigger apoptosis in PC3 prostate cancer cells through Bax activation at a novel activation site, poster presentation at Royal Society of Chemistry 2nd Symposium on Chemical Biology for Drug Discovery 2012, Macclesfield, Manchester, UK

2011

[1] Elsawy M., Martin L., Walker B., Truncation of a 20-mer wild type BIM BH3 domain peptide: identification of the minimum sequence necessary for promoting cell death of prostate cancer (PC3) cells, Biopolymers (Peptide Science) 2011; 96 (4): 472-472, poster presentation at the 22nd American Peptide Symposium, California, San Diego, USA