Molecular self-assembly has been exploited in Nature to develop the complex higher macromolecular structures of both the genome and proteome. My research interests focus on understanding the fundamentals behind peptide self-assembly into bio-inspired structures for the design of novel stable, responsive and functional bionanomaterials with potential various pharmaceutical, biomedical and biotechnological applications.
I have developed novel ultra-short constrained ionic self-complementary peptides that self-assemble into β-sheet nanofibers that were exploited for the fabrication of soft biomaterials such as hydrogels, emulgels, microcapsules and nanoparticles. Recently, I have started exploring the interfacial activity of those self-assembled structures with the potential applications as emulsifiers and as stabilising agents in biopharmaceuticals. Another recent area of interest is using self-assembled peptide microcapsules for encapsulation of stem cells as safe vehicles for cell therapy application.
- Drug functionalised peptide nanofibers for cancer therapeutics
- Self-assembling peptide nanofibers as interfacial stabilisation systems for emulsion formulations
- Nano-fibrillised peptide microcapsules for stem cells encapsulation
- Peptide nanoparticles for targeted drug delivery
- Self-assembling peptide nanofibers as protein aggregation suppressors in Biopharmaceuticals